Epidemiology of basal cell carcinoma in the United Kingdom: incidence,lifestyle factors,and comorbidities |
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| Authors: | D Reinau C Surber S S Jick C R Meier |
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| Affiliation: | 1.Basel Pharmacoepidemiology Unit, Division of Clinical Pharmacy and Epidemiology, Department of Pharmaceutical Sciences, University of Basel, Spitalstrasse 26, Basel CH-4031, Switzerland;2.Hospital Pharmacy, University Hospital Basel, Basel, Switzerland;3.Department of Dermatology, University Hospital Basel, Basel, Switzerland;4.Boston Collaborative Drug Surveillance Program, Boston University School of Public Health, Lexington, MA, USA |
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| Abstract: | Background: Little is known about the epidemiology of basal cell carcinoma (BCC).Methods: Using the Clinical Practice Research Datalink, we calculated annual incidence rates. In a case–control analysis, we examined lifestyle factors and comorbidities.Results: Incidence rose significantly between 2000 and 2011. Basal cell carcinoma risk was increased in alcohol drinkers (slightly) and immunocompromised patients, but reduced in smokers and individuals with abnormal weight.Conclusions: Basal cell carcinoma places a growing public health burden. Lifestyle factors do not play a major role in pathogenesis, but immunosuppression is important. |
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| Keywords: | basal cell carcinoma epidemiology incidence smoking alcohol body mass index comorbidities immunosuppression |
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