| 聚腺苷二磷酸核糖聚合酶抑制剂（PARPi）治疗卵巢癌：影像学研究进展 |
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| 引用本文： | 王艺霖,徐晓娟,陈雁.聚腺苷二磷酸核糖聚合酶抑制剂（PARPi）治疗卵巢癌：影像学研究进展[J].中国医学影像技术,2023,39(4):618-621. |
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| 作者姓名： | 王艺霖 徐晓娟 陈雁 |
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| 作者单位： | 国家癌症中心/国家肿瘤临床医学研究中心/中国医学科学院北京协和医学院肿瘤医院影像诊断科, 北京 100021 |
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| 摘 要： | 聚腺苷二磷酸核糖聚合酶抑制剂(PARPi)的出现，开启了维持治疗卵巢癌的新篇章，使大部分患者预后得到明显改善。影像学可对患者进行非侵入性全面评估，为临床诊治提供重要信息。本文就PARPi作用原理及影像学有关PARPi治疗卵巢癌进展进行综述。
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| 关 键 词： | 卵巢肿瘤 聚腺苷二磷酸核糖聚合酶抑制剂 诊断显像 |
| 收稿时间： | 2022/9/27 0:00:00 |
| 修稿时间： | 2022/12/12 0:00:00 |
Treating ovarian cancer with poly adenosine diphosphate ribosepolymerase inhibitor (PARPi): Progresses of imaging |
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| WANG Yilin,XU Xiaojuan,CHEN Yan.Treating ovarian cancer with poly adenosine diphosphate ribosepolymerase inhibitor (PARPi): Progresses of imaging[J].Chinese Journal of Medical Imaging Technology,2023,39(4):618-621. |
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| Authors: | WANG Yilin XU Xiaojuan CHEN Yan |
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| Institution: | Department of Diagnostic Radiology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China |
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| Abstract: | The emergence of poly adenosine diphosphate ribosepolymerase inhibitor (PARPi) opened up a new chapter for maintenance treatment of ovarian cancer. The application of PARPi significantly improved the prognosis of most patients. Imaging can provide non-invasive, comprehensive assessment of patients, hence providing important information for clinical diagnosis and treatment. The principle of action of PARPi and imaging processes relative to treatment of ovarian cancer with PARPi were reviewed in this article. |
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| Keywords: | ovarian neoplasms poly adenosine diphosphate ribosepolymerase inhibitor diagnostic imaging |
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