On certain changes in the degree of corneal tissue differentiation under experimental conditions

Summary Circular burn of the corneal surface reduces the differentiation and induces proliferative growth in the central area in the form of a polyp. Transplants from the cornea with incomplete development, mature rapidly, after being placed between the superficial layers of the corneal stroma. Nerve branches growing into the transplant are visible in the preparations impregnated according to Campos. In the same transplants placed between the deep corneal layers, where the nervous apparatus is poor developed, the degree of differentiation is decreased and follows the type of the tissue culture in vivo. It is suggested that the degree of the tissue differentiation and its functional adequacy are maintained by the nervous apparatus, whereas denervation provokes tissue autonomism, i.e., reduction of differentiation and acceleration of tissue growth.(Presented by Active Member of the Akad. Med. Nauk SSSR N. A. Kraevskii) Translated from Byulleten' Éksperimental'noi Biologii i Meditsiny, Vol. 56, No. 7, pp. 99–103, July, 1963