视网膜静脉阻塞的多焦振荡电位

目的 探讨多焦振荡电位(multifocal oscillatory potentials, MOPs)在视网膜静脉阻塞中的临床应用价值。 方法 应用VERIS 4.0视诱发反应图像系统检测视网膜静脉阻塞患者19例19只眼，其中视网膜中央静脉阻塞(central retinal vein occlusion, CRVO)8例8只眼，视网膜分支静脉阻塞(branch retinal vein occlusion, BRVO)11例11只眼。20例正常人作为本组患者的正常对照组。放大器通频带的低频截止为100 Hz，高频截止为1 000 Hz。检测试野的水平视角为±26.6°，垂直视角为±22.1°，于4 min(分8段)记录103个六边形的视网膜反应。 结果 无论在整个测试区或分成五个环，正常眼的一阶反应于37 ms内，二阶反应的第一部分于47 ms内可见三个振荡电位OP-1，OP-2，OP-3，二阶反应振荡波形较一阶反应更明确。视网膜中央静脉阻塞和视网膜分支静脉阻塞患者有91.6%(66/72)的OP-1，OP-2和OP-3潜伏期较正常的延迟，68.1%(49/72) 的OP-1，OP-2和OP振幅较正常的降低，视网膜中央静脉阻塞较视网膜分支静脉阻塞的改变更明显。 结论 MOPs能有效和定量评价视网膜静脉阻塞患者不同区域的视网膜功能。 （中华眼底病杂志，2002，18：20-22）

Multifocal oscillatory potentials in retinal vein occlusion

Objective To explore the clinical application value of multifocal oscillatory potentials (MOPs) in retinal vein occlusion (RVO). Methods MOPs were tested using VERIS 4.0 visual evoked response imaging system for 19 cases (19 eyes) of RVO，among them 8 cases of central retinal vein occlusion (CRVO) and 11 cases of branch retinal vein occlusion (BRVO). Twenty normal subjects were as normal control group. The stimulative visual angles subtended ±26.6°horizontally and ±22.1°vertically. The filter setting was bandpass 100～1000 Hz. The retinal responses from 103 hexagons were recorded in 4 min (8 segments). Results In normal control group, OP-1, OP-2 and OP-3 were recorded during 37 ms for first order and 47 ms for second order first slice in whole test field and 5 ring retinal regions, the oscillatory wave shapes of second order were clearer than those of first order. In RVO groups, 91.6% latencies of OP-1, OP-2 and OP-3 were delayed, and 70.8% amplitudes of OP-1, OP-2 and OP-3 were reduced. The delay of the latencies and the decrease of the amplitude in CRVO were more markedly than those in BRVO. Conclusion MOPs can be effectively and quantitatively used to evaluate the retinal function of the different location in RVO.(Chin J Ocul Fundus Dis,2002,18:20-22)