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放宽心脏移植供、受者年龄的可行性研究
引用本文:洪丰,翁渝国,梁红,P.Miralem,H.Roland. 放宽心脏移植供、受者年龄的可行性研究[J]. 中华器官移植杂志, 2000, 21(5): 262-263
作者姓名:洪丰  翁渝国  梁红  P.Miralem  H.Roland
作者单位:1. 暨南大学医学院附属第一医院胸心外科,广州,510630
2. Department of Cardiothoracic and Vascular surgery,German Heart Institute Berlin
摘    要:目的 探讨临床上放宽心脏移植供、受者年龄的可行性。方法 回顾分析989例心脏移植的临床资料,比较供、受者的年龄对术后受者存活率的影响。结果 供者年龄(大于55岁和小于55岁比较)对术后受者存活率的影响不显著(P=0.99),受者年龄(大于60岁和小于60岁比较)对术后其存活率的影响也不显著(P=0.10);另外,供心冷缺血时间也可适当延长。结论 在严格掌握指征的前提下,可适当放宽心脏移植供、受者的

关 键 词:心脏移植 存活率 供体 受体 年龄 可行性研究

Feasible study on expanding selection criteria for donor and recipient undergoing cardiac transplantation
HONG Feng,WENG Yuguo,LIANG Hong,P.Miralem,H.Roland. Feasible study on expanding selection criteria for donor and recipient undergoing cardiac transplantation[J]. Chinese Journal of Organ Transplantation, 2000, 21(5): 262-263
Authors:HONG Feng  WENG Yuguo  LIANG Hong  P.Miralem  H.Roland
Abstract:Objective In order to improve the condition of shortage of donor organs for heart transplantation, the partial selective criteria for potential recipients and donors could be suitably broa- dened . Methods The clinical data of 989 cases undergoing heart transplantation between 1986 and 1997 were studied retrospectively. The effects of age of the patients on the survival of the recipients after operation were compared. Results There were no significant difference in survival rate between 58 cases who received donor hearts from donors with age higher than 55 years and 931 cases who received donor hearts from donors with age lower than 55 years ( P > 0.05 ). Furthermore, there were also no significant difference in survival rate between 119 cases of recipients with age higher than 60 years and 870 cases with age lower than 60 years ( P < 0.05 ). Conclusions The heart transplantation provides more effective treatment for many end-stage heart diseases due to the selective criteria for potential recipients and donors is suitably broadened.
Keywords:Heart transplantation  Patient selection  Treatment outcome  Survival analysis
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