肺癌乳腺癌病人的生活质量及其相关因素分析

目的：在前期研究的基础上进一步探讨癌症病人的生活质量状况，肺癌、乳腺癌病人生活质量的特点，以及可能的影响因素。方法：选用生活质量问卷（QLQ-C30，QLQ-LCl3，QLQ-BR23）作为主要测查工具，采用序列回归统计方法，对246名化疗或放疗的病人进行了分析。结果：肺癌和乳腺癌病人除认知功能和腹泻症状外，各项生活量指标均没有显著性差异，但卡氏功能（KPS）乳腺癌病人明显好于肺癌病人人；癌症病人教育、年龄和经济状况三个因素总的贡献率对整体生活质量(QL)为4%，对情绪功能（EF）为11%，对躯体功能（PF）没有贡献；其中经济因素对EF的单独贡献率为10%。结论：乳腺癌病人的功能状况好于肺癌病人，但生活质量的大多数指标没有显著差异；经济因素对癌症病人情绪的影响不容忽视。

Quality of Life and Its Related Factors in Lung or Breast Cancer Patients

Objective: To assess the quality of life (QoL) and related factors in lung and breast cancer patients. Methods: Quality of Life Questionnaires (QLQ-C30, QLQ-LC13, QLQ-BR23) were used as main indicators of QoL in 246 lung and breast cancer patients prepared for chemotherapy or radiotherapy. Sequential Regression was performed to analyse the effects of factors related to QoL. Results: Most indexes of QLQ-C30 showed no significant difference between lung cancer patients and breast cancer patients except on cognitive function (CF); breast cancer patients, score of Karnofsky Performance Status (KPS) was significantly higher than the lung cancer patients. The total contribution of three factors (education, age and financial condition) is 4% to global quality of life (QL), 11% to emotional function (EF), and the unique contribution of financial condition is 10% for EF. Conclusion: Most indexes of QoL showed no significant difference between lung cancer and breast cancer patients. The performance status of breast cancer patients is better than that of lung cancer patients.