大肠癌372例临床分析

目的探讨扬州地区大肠癌临床发病特点及青年人和老年人大肠癌病例特点比较。方法分析我院近6年大肠癌患者住院病历进行回顾性调查,并比较青年组、老年组大肠癌临床病理上的差异。结果男、女性别比为1.46∶1,平均发病年龄（62.7±12.6）岁。血便、腹痛、贫血是主要临床表现。青年组腹痛发生频率高于老年（χ^2=4.20,P〈0.05）,贫血发生频率低于老年组（χ^2=9.03,P〈0.05）。直肠为好发部位（占50.3%）。组织学类型主要为高、中分化腺癌,占75.3%。青年组低分化腺癌、黏液腺癌、印戒细胞癌比例高于老年组（χ^2=5.66,P〈0.05）。根据Dukes分期,B、C和D 3期共占90.5%。青年组C、D期高于老年组（χ^2=8.93,P〈0.01）。结论大肠癌的发病率上升;青年患者腹痛多见,恶性程度高,分期晚。老年患者贫血多见,癌肿分化好。提高对青年人大肠癌的认识,对疑似病例及早行结肠镜检查有助于早期诊断。

Retrospective analysis on pathological features of 372 patients with coloretal cancer

Objective To explore the clinical characteristics of colorectal cancer in Yangzhou region and comparative study of the characteristics in young and old patients with colorectal cancer.Methods Three hundred and seventy-two cases with colorectal cancer proven by histopathological examination were enrolled from January,2004 to December,2009 in this study.Clinical characteristics of all patients including mean age of episode,clinical nature,location,type of histopathology,and Dukes' stage of tumor were analyzed...