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血清抗苗勒氏管激素检测在多囊卵巢综合征中的临床应用
引用本文:徐金龙,王依屹,蒋国静,张珏.血清抗苗勒氏管激素检测在多囊卵巢综合征中的临床应用[J].国际检验医学杂志,2017,38(1).
作者姓名:徐金龙  王依屹  蒋国静  张珏
作者单位:1. 上海中医药大学附属曙光医院检验科 201203;2. 上海中医药大学附属曙光医院产科 201203
基金项目:上海市加快中医药事业建设发展三年行动计划“研究型中医医院建设”项目子课题
摘    要:目的评价分析抗苗勒氏管激素(AMH)检测在多囊卵巢综合征中的临床应用价值。方法分别检测480例多囊卵巢综合征(PCOS)患者和500例健康女性的抗苗勒氏管激素(AMH),比较AMH在PCOS患者和健康人群中的结果。结果 PCOS患者组血清AMH、血清黄体生成素(LH)、睾酮(T)明显高于对照组,且差异有统计学意义(P0.05);而雌二醇(E_2)促卵泡激素(FSH)与对照组比较,差异无统计学意义(P0.05);随着年龄的增加,AMH水平呈显著下降趋势。结论 AMH水平在PCOS患者中显著高于健康者,并且AMH的水平随着年龄的增加而下降。

关 键 词:抗苗勒氏管激素  多囊卵巢综合征  黄体生成素

The clinical application of detecting anti Mullerian hormone in the patients with PCOS
XU Jinlong,WANG Yiyi,JIANG Guojing,ZHANG Jue.The clinical application of detecting anti Mullerian hormone in the patients with PCOS[J].International Journal of Laboratory Medicine,2017,38(1).
Authors:XU Jinlong  WANG Yiyi  JIANG Guojing  ZHANG Jue
Abstract:Objective To analyze the clinical application of detecting anti Mullerian hormone (AMH) in the patients with polycystic ovary syndrome (PCOS).Methods A total of 480 cases with PCOS and 500 cases of healthy females were selected in the study.The levels of AMH in the patients with PCOS were compared between the two groups.Results The levels of AMH,luteinizing hormone (LH),testosterone (T) in patients with PCOS were significantly higher than those in the healthy control group (P<0.05).Differences of the levels of estradiol (E2) and follicle-stimulating hormone (FSH) in patients with PCOS and thosein healthy control group had no statistical significance(P>0.05).As the age increased,the level of AM H obviously declined.Conclusion The level of AMH in patients with PCOS is obviously higher than that in the healthy ones,it declines with the age increasing.
Keywords:anti Mullerian hormone  polycystic ovary syndrome  luteinizing hormone
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