长沙市成人血细胞分析参考值范围的验证和建立

目的验证长沙地区引用WS/T 405-2012行业标准血细胞分析报告指标参考值范围并建立适宜该地区的研究参数的参考值范围。方法按照《临床实验室检验项目参考区间的制定》程序分析3 138例参考人群的血细胞分析结果,并与WS/T405-2012行业标准比较。结果报告参数中WBC、Neu#、Mon%、MCHC、PLT、MPV、PCT、P-LCC、P-LCR、InR‰和研究参数中的WBC-D、PDW-SD在男性和女性间差异不具有统计学意义(P0.050);WBC、Neu#、Mon%、MCHC和PLT等5项性别间无差异,指标较标准中的参考值范围变窄;男性血细胞分析指标中的Neu%、RBC、HGB、MCV和MCH等5项指标参考值范围变窄,Bas%、Lym#、Mon#和HCT等4项指标参考值范围下限升高,Bas%、Lym#、Mon#和HCT等4项指标参考值范围上限升高,Eos#和Eos%指标参考值范围上限减低,Lym%下限减低;女性血细胞分析指标中的Neu%、Lym#、Mon#和RBC指标变窄,Bas#和Bas%下限升高,Eos%、Lym%、HGB、MCV和MCH下限减低,Eos#、Eos%、Lym%、HGB、MCV和MCH上限减低而HCT上限升高。结论长沙地区应该有选择性的引用标准的参考值范围,并根据需要建立适用于该地区或本实验室的参考值范围。

Verification and establishment of reference value ranges of blood cells analysis among adults in Changsha City

Objective To verify the indicator reference value ranges of blood cells analytic report by quoting the WS/T 405-2012 industry standard in Changsha area and to establish the reference value ranges of research parameters suitable for local area.Methods The blood cells analytic results in 3138 cases of reference group were analyzed according to the program of the Formulation of Reference Intervals in Clinical Laboratory Detection Items and the results were compared with the WS/T 405-2012 industry standard.Results WBC,Neu#,Mon%,MCHC,PLT,MPV,PCT,P-LCC,P-LCR and InR‰ in the report parameters and WBC-D,PDW-SD in the research parameters had no statistical differences between males and females(P>0.050);WBC,Neu#,Mon%,MCHC and PLT had no difference between genders,the indicators were narrowed compared with the reference value ranges in standard;the reference value ranges of Neu%,RBC,HGB,MCV and MCH in the male blood cells analytic indicators were narrowed,the lower limits of Bas%,Lym#,Mon# and HCT reference value ranges were elevated,the upper limits of Bas%,Lym#,Mon# and HCT reference value ranges were elevated,while the upper limits of Eos# and Eos% reference value ranges were decreased,the Lym% lower limit was decreased;Neu%,Lym#,Mon# and RBC in the female blood cells analytic indicators were narrowed,the lower limits of Bas# and Bas% were increased,the lower limits of Eos%,Lym%,HGB,MCV and MCH were decreased,the upper limits of Eos#,Eos%,Lym%,HGB,MCV and MCH were decreased and the HCT upper limit was elevated.Conclusion The Changsha area should have the reference value ranges of selective quoted standards and establishes the reference value ranges suitable for local area or laboratory.