| 蔡氏扶正消癥汤对胃癌细胞体外生长的影响 |
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| 引用本文： | 尹丽慧,郎玮,叶人,吴建波,蔡慎初. 蔡氏扶正消癥汤对胃癌细胞体外生长的影响[J]. 温州医学院学报, 2006, 36(1) |
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| 作者姓名： | 尹丽慧 郎玮 叶人 吴建波 蔡慎初 |
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| 作者单位： | 1. 温州医学院第一附属医院,医科所,浙江,温州,325000
2. 温州医学院第一附属医院,中医科,浙江,温州,325000 |
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| 基金项目： | 浙江省中医药管理局项目 |
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| 摘 要： | 目的:探讨蔡氏扶正消癥汤对人低分化胃癌细胞BGC-823体外生长的影响.方法:采用四甲基偶氮唑蓝(MTT)还原法检测蔡氏扶正消癥汤对BGC-823生长的影响,并观察蔡氏扶正消癥汤对BGC-823细胞形态的影响.结果:蔡氏扶正消癥汤生药能抑制BGC-823的生长.在实验浓度范围内,随着剂量的增加,抑制作用更加明显;同一剂量下,72 h内药物作用时间越长,抑制作用越明显.结论:蔡氏扶正消癥汤能够抑制低分化胃癌细胞BGC-823的生长.
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| 关 键 词： | 中药复方 胃癌细胞 增殖 |
Effect of Cai''''s-fu-zheng-xiao-zheng-tang on human stomach adenocarcinoma cell line BGC-823 growth in vitro |
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| YIN Li-hui,LANG wei,YE Ren,et al.. Effect of Cai''''s-fu-zheng-xiao-zheng-tang on human stomach adenocarcinoma cell line BGC-823 growth in vitro[J]. Journal of Wenzhou Medical College, 2006, 36(1) |
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| Authors: | YIN Li-hui LANG wei YE Ren et al. |
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| Affiliation: | YIN Li-hui,LANG wei,YE Ren,et al. Medical Science Institute of the First Affiliated Hospital of Wenzhou Medical College. Wenzhou 325011 |
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| Abstract: | Objective: To study the effect of Cai's-fu-zheng-xiao-zheng-tang on human stomach adenocarcinoma cell line BGC-823 growth in vitro. Methods: Growth of Cai's-fu-zheng-xiao-zheng-tang on BGC-823 cells was measured with MTT colorimetric assay after treated by various concentrations of Cai's-fu-zheng-xiao-zheng-tang. Morphological changes of BGC-823 cells were observed under light microscope. Results: Cai's-fu-zheng-xiao-zheng-tang inhibited the growth of BGC-823 cells in dose-dependent manner. From 0h to 72h, Cai's-fu-zheng-xiao-zheng-tang at the same concentration inhibited the growth of BGC-823 cells in time-dependent manner. Conclusion: Cai' s-fu-zheng-xiao-zheng-tang can inhibit growth of BGC-823 cells. |
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| Keywords: | herbal medicinal mixture human gastric carcinoma cell proliferation |
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