阻塞性睡眠呼吸暂停综合征患者心血管危险因素的性别间差异性研究

目的分析不同程度阻塞性睡眠呼吸暂停综合征（OSAS）患者的心血管危险因素特点。比较男性患者与女性患者之间风险因素的特点。方法对120例OSAS患者的临床特点进行比较分析。对心血管危险因素与性别关系进行多元回归分析。结果女性高血压发病率为62%,糖尿病28%,肥胖76%,家族性冠心病史24%,均显著高于男性,差异具有统计学意义（〈0.05）。结论女性OSAS患者的心血管危险因素较男性高,需要进行连续气道正压通气（CPAP）治疗。加强对OSAS高危患者的防治,将有利于降低心血管疾病的风险。

Differentiation of cardiovascular risk factors between male and female among the patients with obstructive sleep apnea syndrome

Objective To analyse the characteristics of cardiovascular risk factors among the patients with obstructive sleep apnea syndrome（OSAS） at different degree, and to compare the differentiation between male and female ones.Methods Clinical characteristics of 120 OSAS patients were analysed and multiple regression was used to analysed the relevance of cardiovascular risk factors and gender.Results Among female patients, the morbidity of high blood pressure, diabetes and obesity was 62%, 28% and 76%, respectively; higher than those of male patients（P0.05）.The rate of family history of coronary disease was 24%,higher than that of male patients（P0.05）.Conclusions The prevalence of cardiovascular risk factors are very high in patients with OSAS needing CPAP, especially in women.It is good for reducing the risk of cardiovascular diseases to prevent and cure the OSAS patients with high risks.