磁共振成像在胎儿异常中的临床应用研究

目的探讨磁共振成像(MRI)在产前诊断胎儿异常中的临床应用价值。方法对2006年3月至2007年10月在中国医科大学附属盛京医院就诊、发现胎儿异常的144例孕妇的超声及磁共振结果进行对比。结果超声诊断的胎儿异常144例,其中侧脑室扩张91例,颅后窝异常24例,消化系统异常7例,泌尿系统异常14例,其他异常8例。结果磁共振检查相对于超声,补充诊断率为56.94%(82例),符合诊断率为43.06%(62例)。其中磁共振诊断脑室扩张(脑积水)中合并其他异常占14.29%(13例),颅后窝扩大中合并其他异常占87.50%(21例)。结论MRI是超声发现胎儿异常的重要验证和补充诊断手段,在产前诊断胎儿缺陷中具有重大的临床价值。

Clinical Application of MRI in Fetal Abnormality

Objective To explore the clinical value of magnetic resonance imaging (MRI) in prenatal diagnosis,especially in congenital anomalies. Methods A total of 144 pregnant women with fetal abnormality who admitted to Shengjing Hospital from March 2006 to October 2007 were included. The results of ultrasonography and MRI were compared. Results The fetal abnormality diagnosed by ultrasonography in 144 cases included cerebral ventricular dilation (n =91),posterior cranial fossa abnormality (n =24),digestive system abnormality (n =7),urinary system abnormality (n =14),and other abnormalities (n =8). Compared with ultrasonography,the supplementary diagnostic rate of MRI was 56.94% (n =82),and the diagnostic coincidence rate was 43.06% (n =62). Among 144 cases,13 cases (14.29%) of cerebral ventricular dilation complicated by other abnormalities and 21 cases (87.50%) of posterior cranial fossa abnormality complicated by other abnormalities were confirmed by MRI. Conclusion MRI is an important supplement to ultrasonography in diagnosing fetal abnormality,especially in the prenatal diagnosis of congenital anomalies.