| 低强度激光疗法作用机制的新进展 |
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| 引用本文： | 郑莉琴,;王瑜华,;陈小钢,;杨洪钦,;张彦定,;谢树森.低强度激光疗法作用机制的新进展[J].中国激光医学杂志,2014(5):233-241. |
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| 作者姓名： | 郑莉琴 ;王瑜华 ;陈小钢 ;杨洪钦 ;张彦定 ;谢树森 |
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| 作者单位： | [1]医学光电科学与技术教育部重点实验室·福建省光子技术重点实验室·激光与光电子技术研究所·福建师范大学光电与信息工程学院,福州市350007; [2]福建省发育与神经生物学重点实验室·福建师范大学生命科学学院,福州市350007; |
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| 基金项目： | 国家重点基础研究发展计划（973计划,2015CB352006）; 国家自然科学基金重点项目（61335011）; 长江学者和创新团队发展计划资助（IRT115）; 福建省教育厅B类项目（JB14023） |
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| 摘 要： | 自1967年开始低强度激光疗法就被世人所知,并且作为一种有效的治疗手段广泛应用于神经科、牙科、眼科及再生医学等方面。本文整理、归纳了近年来有关低强度激光实验研究和临床应用的文献,对低强度激光疗法在治疗炎症、促进伤口愈合、组织再生及缓解肌肉疲劳等方面的细胞分子机制的新进展进行概述。结果发现低强度激光能通过调节细胞因子的分泌、基因的表达、蛋白质合成等达到治疗的目的。了解低强度激光疗法的细胞分子机制对临床应用低强度激光治疗疾病至关重要。
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| 关 键 词： | 低强度激光疗法 炎症反应 伤口愈合 组织再生 肌肉疲劳 作用机制 |
Advances in Mechanisms of Low-level Laser Therapy |
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| Institution: | ZHENG Li-qin, WANG Yu-hua, CHEN Xiao-gang, YANG Hong-qin, ZHANG Yan-ding , XlE Shu-sen(1. Institute of Laser and Optoelectronics Technology, Fujian Provincial Key Laboratory for Photonics Technology, Key Laboratory of OptoElectronic Science and Technology for Medicine of Ministry of Education, Fujian Normal University, Fuzhou 350007, China ;2. Fujian Key Laboratory of Developmental and Neural Biology, College of Life Sciences, Fujian Normal University) |
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| Abstract: | Low-level laser therapy （LLLT） has been known since 1967 and has gained more and more attention in recent years as an effective therapy in neurology, ophthalmology, dentology, regenerative medicine and so on. This review sorts many experimental studies and clinical applications about LLLT published in recent years, and summarizes the advances of the potential mechanisms of LLLT in treating inflammation, promoting wound healing and tissue regeneration, reducing muscle fatigue. It shows that LLLT could treat diseases through modulating cytokines release, gene expression and protein synthesis. The understanding of the cellular and molecular mechanisms of LLLT is of great importance for clinical application of LLLT. |
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| Keywords: | Low-level laser therapy Inflammation Wound healing Tissue regeneration Muscle fatigue Mechanism |
| 本文献已被 CNKI 维普 等数据库收录！ |
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