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Dendritic Cell Paucity Leads to Dysfunctional Immune Surveillance in Pancreatic Cancer
Affiliation:1. Department of Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA;2. Department of Cell Biology and Physiology, Washington University School of Medicine, St. Louis, MO 63110, USA;3. Department of Radiation Oncology, Washington University School of Medicine, St. Louis, MO 63110, USA;4. Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA;5. Howard Hughes Medical Institute, Washington University School of Medicine, St. Louis, MO 63110, USA;6. Department of Surgery, Barnes—Jewish Hospital, St. Louis, MO 63110, USA;7. Alvin J. Siteman Comprehensive Cancer Center, St. Louis, MO 63110, USA
Abstract:
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  • Keywords:dendritic cell  pancreatic cancer  neoantigen  immune surveillance  vaccination  CD40  Flt3L  immunotherapy  radiation therapy
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