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Effect of a single session of transcranial direct-current stimulation on balance and spatiotemporal gait variables in children with cerebral palsy: A randomized sham-controlled study
Authors:Luanda A. C. Grecco  Natália A. C. Duarte  Nelci Zanon  Manuela Galli  Felipe Fregni  Claudia S. Oliveira
Abstract:

Background:

Transcranial direct-current stimulation (tDCS) has been widely studied with theaim of enhancing local synaptic efficacy and modulating the electrical activity ofthe cortex in patients with neurological disorders.

Objective:

The purpose of the present study was to determine the effect of a single sessionof tDCS regarding immediate changes in spatiotemporal gait and oscillations of thecenter of pressure (30 seconds) in children with cerebral palsy (CP).

Method:

A randomized controlled trial with a blinded evaluator was conducted involving 20children with CP between six and ten years of age. Gait and balance were evaluatedthree times: Evaluation 1 (before the stimulation), Evaluation 2 (immediatelyafter stimulation), and Evaluation 3 (20 minutes after the stimulation). Theprotocol consisted of a 20-minute session of tDCS applied to the primary motorcortex at an intensity of 1 mA. The participants were randomly allocated to twogroups: experimental group - anodal stimulation of the primary motor cortex; andcontrol group - placebo transcranial stimulation.

Results:

Significant reductions were found in the experimental group regardingoscillations during standing in the anteroposterior and mediolateral directionswith eyes open and eyes closed in comparison with the control group (p<0.05).In the intra-group analysis, the experimental group exhibited significantimprovements in gait velocity, cadence, and oscillation in the center of pressureduring standing (p<0.05). No significant differences were found in the controlgroup among the different evaluations.

Conclusion:

A single session of tDCS applied to the primary motor cortex promotes positivechanges in static balance and gait velocity in children with cerebral palsy.
Keywords:cerebral palsy   physical therapy   movement   balance   electric stimulation   motor cortex
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