阴道镜下活检与LEEP术病理分析对于宫颈上皮内瘤变的诊断价值

目的:对比分析宫颈上皮内瘤变(CIN)阴道镜下活检与LEEP术后病理结果,探讨两者在诊断和治疗CIN中的价值。方法:回顾性分析155例CIN患者阴道镜下活检与LEEP术后病理的结果,探讨其病理诊断结果的差异。结果:阴道镜下活检为CIN1、CIN2和CIN3与LEEP术后病理结果符合率分别为46.3%、70.8%、82.5%,总符合率为63.2%,升级者25例(16.1%),降级者32例(20.6%),宫颈癌漏诊率为3.2%。结论:阴道镜下活检是对宫颈CIN作出初步诊断的一种简单而有效的方法,但有一定局限性,LEEP术在阴道镜活检基础上起着诊断和治疗CIN的作用,可以弥补阴道镜活检的不足。

Pathological analysis of cervical intraepithelial neoplasia of biopsy by colposcopy and loop electrical excision procedure

Objective To compare the biopsy by colposcopy and loop electrical excision procedure(LEEP) for cervical intraepithelial neoplasia,and to explore the value in the diagnosis and treatment.Method Biopsy by colposcopy and biopsy after LEEP were analyzed retrospectively in 155 cases of cervical intraepithelial neoplasia,and to study the differences of pathological diagnosis results.Results Coincidence rate of pathological results CIN I,CIN II,CIN III between cervical biopsy by colposcopy and LEEP was 46.3%,70.8%,82.5%,respectively,and the total coincidence rate was 63.2%,25 cases upgraded(16.1%),32 cases downgraded(20.6%),the missed diagnosis rate of cervical cancer was 3.2%.Conclusion Cervical biopsy by colposcopy is a simple,effective method in the diagnosis of CIN,but there are some limitations.LEEP plays a diagnostic and therapeutic role based on the biopsy by colposcopy,and can compensate the deficiency of biopsy by colposcopy.