| 2型糖尿病脂肪肝的筛查及相关因素分析 |
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| 引用本文： | 高伟,任瑞珍,唐与晓,王秋灵,王玮,孟晓梅. 2型糖尿病脂肪肝的筛查及相关因素分析[J]. 中华糖尿病杂志, 2005, 13(2): 105-107 |
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| 作者姓名： | 高伟 任瑞珍 唐与晓 王秋灵 王玮 孟晓梅 |
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| 作者单位： | 青岛大学医学院附属烟台毓璜顶医院内分泌科 264000(高伟，任瑞珍，唐与晓，王秋灵，王玮)，青岛大学医学院附属烟台毓璜顶医院内分泌科 264000(孟晓梅) |
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| 摘 要： | 目的 探讨2 型糖尿病(T2DM)伴脂肪肝的患病率与相关因素。 方法 对400 例T2DM患者进行临床、生化、瘦素、C肽与肝脏超声检查。 结果 T2DM患者脂肪肝的患病率为46%,该组的体质指数(BMI)、舒张压显著高于无脂肪肝组(P<0.05),甘油三酯(TG)、1 h与2 h C肽、瘦素水平显著高于无脂肪肝组(P<0.01);Logistic逐步回归分析显示1 h C肽、瘦素、TG水平升高,与脂肪肝的发生呈正相关关系。 结论 T2DM患者脂肪肝患病率明显升高,且与BMI、TG、C肽、瘦素水平呈正相关。
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| 关 键 词： | 2型糖尿病 脂肪肝 T2DM 病毒性肝炎 血管结构 |
| 修稿时间： | 2004-06-17 |
Prevalence and associated factor of fatty liver in type 2 diabetes mellitus |
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| GAO Wei,REN Rui-zhen,TANG Yu-xiao,et al.. Prevalence and associated factor of fatty liver in type 2 diabetes mellitus[J]. CHINESE JOURNAL OF DIABETES MELLITUS, 2005, 13(2): 105-107 |
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| Authors: | GAO Wei REN Rui-zhen TANG Yu-xiao et al. |
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| Affiliation: | GAO Wei,REN Rui-zhen,TANG Yu-xiao,et al. Department of Endocrinology,Yuhuangding Hospital,Yantai,Shandong 264000,China |
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| Abstract: | Objective To study the prevalence and associated factor of fatty liver in type 2 (diabetic) patients. Methods Biochemical test, leptin, C-peptide and liver ultrasound examination were carried in 400 patients. Results The prevalence of fatty liver in type 2 diabetic patients was 46%. The associated factors included leptin, 1-hour C-peptide and TG(r=0.225, 0.046, 0.234, P<0.01). Conclusion Reducing body weight, regulating hyperlipidemia, controlling blood pressure and improving IR can reduce the prevalence of fatty liver. Liver ultrasound is an easy and capable (examination) method for detecting fatty liver. |
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| Keywords: | Diabetes mellitus type 2 Fatty liver Prevalence |
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