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Study of pain response in neonates during venipuncture with a view to analyse utility of topical anaesthetic agent for alleviating pain
Affiliation:1. Graded Specialist (Paediatrics), Military Hospital Nasirabad, Rajasthan, India;2. Head of Department (Paediatrics & Neonatology), Base Hospital Delhi Cantt 10, India;3. House no. 73, Sector 5, Chandigarh 160009, India;4. Graded Specialist (Medicine), Military Hospital Nasirabad, Rajasthan, India;1. Professor & Head, Department of Psychiatry, Armed Forces Medical College, Pune 411040, India;2. Senior Advisor (Psychiatry), Command Hospital (Eastern Command), Kolkatta, India;3. Scientist ''G'', Department of Psychiatry, Armed Forces Medical College, Pune 411040, India;1. Associate Professor, Department of Physiology, Armed Forces Medical College, Pune, 411040 India;2. Head of Department, Space and Environmental Physiology, Institute of Aerospace Medicine, Bengaluru, India;3. Classified Specialist (Community Medicine), O/o DGMS (Navy), New Delhi, India;4. Col Med, HQ 2 Corps, C/o 56 APO, India;1. Associate Professor, Department of Anaesthesiology & Critical Care, Armed Forces Medical College, Pune 411040, India;2. Professor and Head, Department of Anaesthesiology & Critical Care, Armed Forces Medical College, Pune 411040, India;3. Resident, Department of Anaesthesiology, Armed Forces Medical College, Pune 411040, India;4. Consultant (Medicine & Respiratory Medicine), Brig (Med) 21Corps, C/O 56 APO, India;1. Brig i/c Adm, (Military Hospital Cardio Thoracic Centre), Pune 411040, India;2. Graded Specialist (Anaesthesiology), 162 Military Hospital, C/o 99 APO, India;3. Deputy Commandant, Command Hospital (Eastern Command), Kolkata, India;1. Senior Adviser (Radiodiagnosis), Command Hospital (Eastern Command), Kolkata, India;2. Commandant, Military Hospital Kirkee, Pune 411003, India;3. Commanding Officer, 421 Field Hospital, C/o 99 APO, India;4. Commanding Officer, 10 Air Force Hospital, C/o 99 APO, India;5. Consultant & Head (Radiodiagnosis), Army Hospital (R&R), New Delhi, India;1. Graded Specialist (Medicine), Military Hospital Allahabad, UP, India;2. Graded Specialist (Radiology), Military Hospital Dehradun, Uttarakhand, India;3. Graded Specialist (Medicine),155 Base Hospital, C/o 99 APO, India;4. Consultant (Radiodiagnosis & Imaging), Army Hospital (R&R), New Delhi, India
Abstract:
BackgroundNeonates being nonverbal are unable to express their pain leading to underestimation of their pain and hence insufficient pain relief. Neonatal pain is assessed by pain scales based on the behavioural and physiological changes that occur in response to painful stimuli. This cross sectional study was conducted at a tertiary care centre using Premature Infant Pain Profile (PIPP) score with 4% lidocaine as local anaesthetic agent to produce surface anaesthesia of skin prior to intravenous cannulation.MethodsSample size was collected by simple randomisation method. Our study groups included 50 term and 50 preterm neonates with POG of 28–40 weeks requiring IV cannulation. Heart rate (HR), SpO2, facial expressions and behavioural state were noted before venipuncture and after venipuncture using PIPP scale. Same cohort of patients was assessed for pain response after applying 4% lidocaine cream during future venipuncture with help of PIPP score.ResultsThe PIPP score in preterm group before and after anesthesia was 11.28 ± 3.72 and 9.58 ± 3.39. PIPP score in term group before and after anesthesia was 11.54 ± 2.84 and 9.04 ± 2.97. There was reduction in mean PIPP score after using topical anesthetic agent in both study groups and the results were statistically significant.ConclusionThis study found that topical anesthetic agents were effective in reducing pain during venipuncture. Based on the facts of the study, it is recommended that pain scoring should be a part of routine monitoring in neonatal intensive care units and appropriate measures should be used to reduce pain.
Keywords:New Ballard Score  Premature Infant Pain Profile  Period of gestation  Low birth weight  Topical anaesthesia
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