宫颈高危型HPV持续感染患者的中医体质研究

目的:探讨宫颈高危型人乳头痛病毒(HPV)持续感染患者的中医体质,为治疗开辟新思路。方法:参照王琦教授的9种中医体质学说,对研究对象首先进行问卷调查,填写中医体质评估表,然后运用中医体质评估系统进行评估,分析得出中医体质结果,对中医体质评估结果进行归纳总结。结果:宫颈高危型HPV持续感染161例(21.32%),最小年龄21岁,最大年龄50岁,平均年龄(33.23±4.38)岁。慢性炎症90例(55.90%),CINⅠ47例(29.19%),CINⅡ24例(14.91%)。HPV-52、HPV-53、HPV-58、HPV-56、HPV-16、HPV-18为主要感染亚型。中医体质评估结果:痰湿质45例(27.95%),湿热质37例(22.98%),气虚质28例(17.39%),阳虚质24例(14.91%),上述4种体质为宫颈高危型HPV持续感染者的主要体质类型。结论:宫颈高危型HPV持续感染患者的中医体质均为偏颇体质,尤其以痰湿质、湿热质、气虚质、阳虚质最为常见。

A study on TCM constitution of patients with persistent cervical high-risk HPV infection

Objective:The aim is to explore the TCM constitution of patients with persistent high-risk HPV infection in the cervix and to open up new ideas for the treatment of high-risk HPV infection in the cervix.Methods:According to Professor Wang Qi’s 9 kinds of TCM constitutional theory,the subjects were firstly surveyed,filled out the TCM constitutional quantitative table,and then were evaluated by TCM constitution evaluation system to obtain TCM constitution results.Finally,all the subjects’TCM constitution results were studied and summarized.Results:A total of 161(21.32%)patients with high-risk HPV infection were enrolled.The minimum age was 21 years old,the maximum age was 50 years old,and the average age was 33.23±4.38 years old.There were 90(55.90%)cases of chronic inflammation,47(29.19%)cases of CINI,and 24(14.91%)cases of CINII.Among them,such subtypes as HPV-52,HPV-53,HPV-58,HPV-56,HPV-16,HPV-18 were the main infection subtypes.TCM constitutional evaluation results:45(27.95%)patients had the constitution of phlegm-dampness,37(22.98%)patients had the constitution of damp-heat,28(17.39%)patients had the constitution of qi deficiency,and 24(14.91%)patients had the constitution of yang deficiency.The constitutions of phlegm-dampness,damp-heat,qi deficiency,and yang deficiency were the main constitutions of the patients with persistent high-risk HPV infection in the cervix.Conclusions:The TCM constitution of patients with persistent high-risk HPV infection is biased,the constitutions of phlegm-dampness,damp-heat,qi deficiency,and yang deficiency were the main constitutions of the patients with persistent high-risk HPV infection in the cervix.