Synthesis and anti-inflammatory activity of substituted (E)-4-phenyl-3-buten-2-ones |
| |
| Affiliation: | 1. State Key Laboratory of Applied Organic Chemistry, College of Chemistry and Chemical Engineering, Lanzhou University, Lanzhou 730000, China;2. College of Chemical Engineering, Northwest Minzu University, Lanzhou 730030, China |
| |
| Abstract: | ![]()
A series of ring substituted 4-phenyl-3-buten-2-ones was synthesized and evaluated for anti-inflammatory activity by carrageenan-induced paw edema in rats. Several compounds showed significant activity, among them, the 4-acetyloxy-3-methoxy derivative was the most active and the 4-methoxy derivatives were the least effective. |
| |
| Keywords: | |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
