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少年、儿童垂体腺瘤的经蝶窦显微外科手术治疗(附21例报告)
引用本文:杨义,任祖渊,苏长保,王任直,马文斌. 少年、儿童垂体腺瘤的经蝶窦显微外科手术治疗(附21例报告)[J]. 中国微侵袭神经外科杂志, 2003, 8(9): 403-405
作者姓名:杨义  任祖渊  苏长保  王任直  马文斌
作者单位:中国医学科学院北京协和医院神经外科,北京,100730
摘    要:目的 探讨年龄小于14岁的少年、儿童垂体腺瘤的诊断及其经蝶窦显微外科于术治疗。方法 本组21例,其中垂体ACTH腺瘤11例,PRL腺瘤4例,GH腺瘤3例,无功能腺瘤3例。均行经蝶窦显微外科垂体腺瘤切除术。结果 随诊1~10年,治愈76.2%、缓解14.3%,复发9.5%。结论 经蝶窦垂体腺瘤切除术是治疗儿童垂体腺瘤的最佳方法。少年儿童垂体腺瘤以ACTH腺瘤最多见,除GH腺瘤以外多有发育迟缓,女性多有闭经或月经紊乱。

关 键 词:少年 儿童 垂体腺瘤 经蝶窦手术 显微外科 术后并发症
文章编号:1009-122X(2003)09-0403-03
修稿时间:2003-05-24

Transsphenoidal microsurgery for children with pituitary adenomas
YANGYi,RENZuyuan,SU Changbao,et al Departmentof Neurosurgery,BeijingUnionHospital,ChineseAcademyof MedicalSciences,Beijing,China. Transsphenoidal microsurgery for children with pituitary adenomas[J]. Chinese Journal of Minimally Invasive Neurosurgery, 2003, 8(9): 403-405
Authors:YANGYi  RENZuyuan  SU Changbao  et al Departmentof Neurosurgery  BeijingUnionHospital  ChineseAcademyof MedicalSciences  Beijing  China
Affiliation:YANGYi,RENZuyuan,SU Changbao,et al Departmentof Neurosurgery,BeijingUnionHospital,ChineseAcademyof MedicalSciences,Beijing100730,China
Abstract:Objective To discuss the diagnosis and surgical treatment in children with pituitary tumors under14years old.Methods 21children under14years old with pituitary tumors were performed transsphenoidal microsurgery.12were diagnosed as adrenocorticotropic hormone-releasing adenomas(Cushing's diseases),4prolactinomas,3were growth hormone-releasing adenomas,2nonactive pituitary adenomas.Postoperative complications include polyuria in7cases and disorder confused electrolyte balances in8cases.Results Postoperative follow-up were1to10yearsinallthepatients.Thecurerateinthisserieswas76.2%,emissionratewas14.3%andrecurrencerate9.5%.Conclusion The trannsphenoidalmicrosurgeryis safeandsuccessfulfor pituitarytumorsin children.Pituitaryadnomasin childrenaremostlikelypituitary ACTH-releasingmicroadenomas.Growtharrestis commoninchildrenwithpituitaryadenomasexceptof pituitaryGHadenomasandprimary amenorrheaor menorrheadisorderarecommoninfemales.
Keywords:pituitaryadenomas  children  diagnosis  transsphenoidalmicrosurgery  
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