Content of HSP70 in rats with hereditary stress-induced arterial hypertension |
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| Authors: | G V Petrova V A Adarichev A A Krivenko G S Dymshits A L Markel' G S Yakobson |
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| Institution: | (1) Institute of Physiology, Siberian Division of the Russian Academy of Medical Sciences, Novosibirsk;(2) Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Sciences, Novosibirsk |
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| Abstract: | Sensitivity of normotensive Wistar rats and NISAG rats (with hereditary arterial hypertension) to heat stress is compared
at the organism and cell levels. High temperature sensitivity of NISAG rats correlates with a low content of the main heat
shock protein HSP70. This relationship can serve as a biochemical marker of predisposition to arterial hypertension.
Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 124, No. 8, pp. 171–173, August, 1997 |
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| Keywords: | arterial hypertension thermosensitivity heat shock proteins restriction fragment length polymorphism analysis |
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