Galaxy: a platform for interactive large-scale genome analysis |
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| Authors: | Giardine Belinda Riemer Cathy Hardison Ross C Burhans Richard Elnitski Laura Shah Prachi Zhang Yi Blankenberg Daniel Albert Istvan Taylor James Miller Webb Kent W James Nekrutenko Anton |
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| Affiliation: | Center for Comparative Genomics and Bioinformatics, Huck Institutes for Life Sciences, Penn State University, University Park, Pennsylvania 16802, USA. |
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| Abstract: | Accessing and analyzing the exponentially expanding genomic sequence and functional data pose a challenge for biomedical researchers. Here we describe an interactive system, Galaxy, that combines the power of existing genome annotation databases with a simple Web portal to enable users to search remote resources, combine data from independent queries, and visualize the results. The heart of Galaxy is a flexible history system that stores the queries from each user; performs operations such as intersections, unions, and subtractions; and links to other computational tools. Galaxy can be accessed at http://g2.bx.psu.edu. |
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