布拉氏酵母菌联合左氧氟沙星治疗成人急性感染性腹泻临床疗效观察

目的观察布拉氏酵母菌联合左氧氟沙星治疗成人急性感染性腹泻的临床疗效。方法 120例成人急性腹泻者随机分为两组,治疗组采用布拉氏酵母菌联合左氧氟沙星治疗,共60例,对照组采用左氧氟沙星治疗,共60例。结果治疗组总有效率为96.67%,对照组为78.33%,两组比较差异有统计学意义（Х^2=9.22,P〈0.05）。腹泻平均持续时间治疗组为（1.68±0.30）d,对照组为（2.13±0.35）d,两组比较差异有统计学意义（P〈0.05）;服药第3天,治疗组日平均大便次数为（1.48±0.14）次,对照组为（1.51±0.11）次（P〉0.05）,两组比较差异均无统计学意义。结论布拉氏酵母菌联合左氧氟沙星是成人急性腹泻的有效治疗手段,可以缩短成人急性腹泻的持续时间,改善腹泻症状。

The clinical observation on the effectiveness of saccharomyces boulardii plus levofloxacin in adult with acute infectious diarrhea

Objective To assess the efficacy of Saccharomyces boulardii plus levofloxacin in adult with acute infection diarrhea.Methods 120 cases adults suffering from acute diarrhea were divided into 2 groups,Saccharomyces boulardii plus levofloxacin 60 cases,levofloxacin 60 cases.Results The total effective rate in the above groups were 96.67% and 81.67% respectively,comparison between the two groups showed significance（Х^2=9.22,P〈0.05）;the mean diarrhea duration was（1.68±0.30）days in the treated group and（2.13±0.35） days in the controlled group,comparison between the two groups showed significance（P〈0.05）;On the 3rd day,the patients in the treated group passed（1.48±0.14）stools/day versus（1.51±0.11） stools/day in controlled group（P〈0.05）,comparison between the two groups showed nonsignificance.Conclusion Saccharomyces boulardii plus levofloxacin was effective for the treatment of acute infection diarrhea in adult,and it can decrease the duration of diarrhea,improve the acute diarrhea symptoms and reduced the risk of prolonged diarrhea.