Nickel penetration in allergic individuals: bioavailability versus X-ray micro-analysis detection |
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| Authors: | Kirsti,Kalimo ,Kaija,Lammintausta ,Jouko,Mä ki ,Juhani,Teuho Christer T.,Jansé n |
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| Affiliation: | Department of Dermatology, University of Turku, Turku, Finland;Laboratory of Electron Microscopy, University of Turku, Turku, Finland;Wihuri Physical Laboratory, University of Turku, Turku, Finland |
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| Abstract: | ![]()
Development of local allergic reactions after different application times with Finn Chambers was recorded in 34 nickel-sensitive patients. Biologically significant amounts of nickel seemed to penetrate the skin within a few hours, although physical penetration was minimal. Nickel was detected only in the upper keratin cell layer with an X-ray microanalysis method. |
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| Keywords: | Nickel pentration-bioavailability |
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