| 急性淋巴细胞白血病伴髓系抗原表达的免疫分型特点 |
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| 引用本文： | 杨晓红,廖军鲜,许勇钢,钟明华,唐旭东,陈艳荣,徐韶华,刘锋,麻柔. 急性淋巴细胞白血病伴髓系抗原表达的免疫分型特点[J]. 中日友好医院学报, 2005, 19(6): 347-350 |
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| 作者姓名： | 杨晓红 廖军鲜 许勇钢 钟明华 唐旭东 陈艳荣 徐韶华 刘锋 麻柔 |
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| 作者单位： | 1. 中国中医研究院西苑医院,血液科,北京,100091
2. 中日友好医院,血液科,北京,100029 |
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| 摘 要： | 目的:探讨急性淋巴细胞白血病(ALL)伴髓系抗原(My)表达的免疫表型特点及进行相关分析.方法:对85例初诊ALL患者进行免疫学分型,以My阳性/阴性( /-)对B细胞ALL(B-ALL)和T细胞ALL(T-ALL)进行组间分析.结果:My B-ALL和My T-ALL患者的CD13及CD33的中位数均高于My-B-ALL和My-T-ALL患者,其表达率均显著高于My-B-ALL和My-T-ALL患者(P＜0.01,P＜0.05).My B-ALL患者的CD15的中位数高于My-B-ALL患者,表达率显著高于My-B-ALL患者(P＜0.01).CD13、CD15、CD33的相关性在组间具有显著性差异(P＜0.01).结论:ALL中My的表达与mAb克隆、细胞染色技术、样本来源、阳性界值等多种因素有关.
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| 关 键 词： | 白血病,淋巴细胞,急性 免疫表型分型 抗原 流式细胞术 |
| 文章编号： | 1001-0025（2005）06-0347-04 |
| 收稿时间： | 2005-08-10 |
| 修稿时间： | 2005-09-21 |
Analysis on the immnunophenotype of acute lymphoblastic leukemia with myeloid antigen expression |
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| YANG Xiao-hong,LIAO Jun-xian,XU Yong-gang. Analysis on the immnunophenotype of acute lymphoblastic leukemia with myeloid antigen expression[J]. Journal of China-Japan Friendship Hospital, 2005, 19(6): 347-350 |
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| Authors: | YANG Xiao-hong LIAO Jun-xian XU Yong-gang |
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| Affiliation: | National Hematological Medical Center of TCM,Xiyuan Hospital affiliated to China Academy of Traditional Chinese Medicine,Beijing, 100091,China |
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| Abstract: | Objective:To discuss the immunophenotype characteristics of acute lymphoblastic leukemia(ALL)with myeloid antigen(My)expression and relative analysis.Methods:Eighty five cases with ALL were typed on immunology and dealt with My+/-B-ALL and T-ALL.Results:The medians of CD13 and CD33 of My+B-ALL and My+T-ALL were all higher than My-B-ALL and My-T-ALL(P<0.01,P<0.05).The median of CD15 in My+B-ALL was substantially higher than that in My-B-ALL(P<0.01).The relativity among CD13,CD15 and CD33 was statistically different(P<0.01).Conclusion:The expression of My is related with mAb clone,cell staining technique,case resource and positive threshold. |
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| Keywords: | leukemia, lymphoblastic, acute immunophenotype antigens cytometry |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
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