老年不稳定性心绞痛98例临床分析

目的：探讨老年不稳定性心绞痛患者的治疗方法。方法：回顾性分析98例不稳定性心绞痛患者的临床资料，50例采用阿司匹林100mg和氯吡格雷75mg（双抗）＋抗凝进行治疗，48例采用单纯阿司匹林100mg（单抗）＋抗凝进行治疗，分析并比较双抗＋抗凝纽和单抗＋抗凝组的疗效。结果：双抗＋抗凝组好转45例（90％），恶化4例（8％），死亡1例（2％），半年复发率为5％。单抗＋抗凝组好转33例（68％），恶化14例（30％），死亡1例（2％），半年复发率为30％。结论：小剂量双抗治疗高龄不稳定性心绞痛患者相对安全，可明显改善其临床症状及预后，双抗治疗疗效优于单抗治疗，合并高血压、糖尿病、感染的患者恫时要治疗基础疾病。

Treatment of unstable angina pectoris in elderly

Objective:To investigate the treatment of unstable angina pectoris elderly patients. Methods:Clinical data of 98 elderly patients with unstable angina pectoris treated with different regimen were studied retrospectively,including 50 patients in group A treated with aspirin 100 mg and clopidogrel 75 mg and anticoagulant agent,48 patients in group B treated with aspirin alone 100 mg and anticoagulant agent,the effects were compared. Results:After treatment,the improved rate,worse rate,death rate and recurrence rate of half a year in group A and B were 90% (45/50),68%(33/48),and 8%(4/50),30%(14/48),and 2%(1/50),2%(1/48),and 5%,30% respectively. Conclusion:Treatment of elderly patients with unstable angina using low-dose double anticoagulant agents has better effect than single anticoagulant agent,which is relatively safe and can significantly improve the clinical symptoms and prognosis; for the patients with hypertension,diabetes and infection,simultaneous treatment of the original diseases is required.