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Role of vagus nerves in antiarrhythmic effect of DAGO in acute myocardial ischemia |
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| Authors: | S. D. Mikhailova G. I. Storozhakov N. A. Bebyakova T. M. Semushkina |
| Affiliation: | (1) Russian State Medical University, Moscow |
| Abstract: | Acute experiments on cats show that DAGO, a selective μ-opiate receptor agonist, elicits a pronounced antiarrhythmic effect in ischemia-induced arrhythmias. The protective effect of DAGO is observed only under conditions of intact parasympathetic innervation of the heart and apparently depends on then. vagus activity and stimulating effect of DAGO on acetylcholine release. Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 124, No. 10, pp. 377–379, October, 1997 |
| Keywords: | DAGO μ -opiate receptors myocardial ischemia cardiac arrhythmias vagus nerves |
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