高温和噪声环境对飞行员红细胞膜脂质过氧化的损害

目的 搪塞高温和噪声等飞行环境对飞行员红细胞膜脂质过氧化的影响。方法 用分光光度计法测定２４名飞行员,飞行前、飞行后即刻以及飞行后８ｈ的红细胞膜谷胱甘肽过氧化物酶及丙二醛（ＭＤＡ）的含量,并与对照组进行比较。结果垢即刻红细胞膜中的谷胱甘肽过氧化物酶活力明显低于对照组,飞行后即刻和飞行后８ｈ的二醛含量明显高于普通地面人员。结论高温和噪声等飞行环境可导致飞行员红细胞膜脂质过氧化反应增强和抗氧化能力降低

Effects of Heat and Noise Environments on Lipid Peroxidation Erythrocyte Membrane in Pilots

Objective To investigate the effects of heat and noise environments on lipid peroxidation of erythrocyte membrane in pilots. Method Twenty four pilots and twenty one ground personnel (control group) served as the subjects. The pilots performed flying in heat and noise environments. Glutathione peroxidase(GSHpx) and malondiadehyde(MDA) levels in erythrocyte membrane were determined before flying(6:00 a.m.), immediately after flying(12:00 a.m.) and 8 hours after flying (8:00 p.m.) respectively with a spectrophotometer. Result Immediately after flying, GSHpx activity in pilot's erythrocyte membrane decreased significantly as compared with that in control group.Immediately after flying and 8h after flying, MDA contents in pilots increased significantly as compared with that of control group. Conclusion Heat and noise environments might induce increase of lipid peroxidation reaction and decrease of antioxidant ability.