湖南省35~75岁居民心血管病高危人群流行特征

  目的  了解湖南省35~75岁居民心血管病高危人群流行病学特征，为心血管病防治提供依据。  方法  利用湖南省心血管病高危人群早期筛查与综合干预项目数据分析心血管病高危人群流行病学特征，通过拟合多变量混合效应模型来评估个体特征与心血管病高危风险之间的关联。  结果  共纳入99 001名调查对象，平均年龄(56.6±9.7)岁，62.2%为女性。心血管病高危人群占比12.1%，高危人群中有96.4%患有高血压。生活在农村(r=0.036)、民族为汉族(r=0.012)、饮酒(r=0.041)、超重(r=0.110)和肥胖(r=0.086)都与心血管病高危风险呈正相关，而高学历(r=-0.040)、高家庭收入(r=-0.032)和已婚(r=-0.027)与心血管病高危风险呈负相关(均有P < 0.001)。  结论  湖南省筛查出心血管病高危人群的比例较高，应重点针对其采取健康教育和综合干预措施，以减少全省居民心血管病发病风险。

Epidemiological characteristics of high-risk population of cardiovascular disease in residents aged 35-75 years in Hunan Province

  Objective  To understand epidemiological characteristics of high-risk population of cardiovascular disease in adults aged 35-75 years in Hunan Province, and to provide basis for prevention and treatment of cardiovascular diseases.  Methods  Epidemiological characteristics of high-risk population of cardiovascular disease were analyzed through the data from China Patient-Centered Evaluative Assessment of Cardiac Events (PEACE) Million Persons Project in Hunan Province. The mixed model was used to analyze the association between individual characteristics and high risk of cardiovascular disease.  Results  Totally, 99 001 participants were enrolled in this study, with an average age of (56.6±9.7) years. In both sexes, 62.2 % of participants were females and 37.8% were males. 12.1% of the participants were the high-risk population for cardiovascular diseases, and among these high-risk population, 96.4% people had been diagnosed with hypertension. Living in rural areas, Han nationality, drinkers and overweight/obesity were positively correlated with the risk of cardiovascular disease, while those with high education, high family income and married were negatively correlated with the risk of cardiovascular disease (all P < 0.001).  Conclusions  The proportion of high-risk population of cardiovascular disease screened in Hunan Province is high. Comprehensive intervention measures should be taken to reduce the risk of cardiovascular disease among high-risk population.