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Changes in the leucocyte count during and after brief intense exercise
Authors:D. A. McCarthy  I. A. Macdonald  H. A. Shaker  P. Hart  S. Georgiannos  J. Deeks  A. J. Wade
Affiliation:(1) School of Biological Sciences, Queen Mary and Westfield College, Mile End Road, E1 4NS London, UK;(2) Department of Physiology and Pharmacology, University of Nottingham, Queens Medical Centre, NG7 2UH Nottingham, UK;(3) Department of Sports Medicine, London Hospital Medical College, E1 2AD London, UK;(4) Department of Nephrology, London Hospital Medical College, E1 2AD London, UK;(5) Department of Surgery, London Hospital Medical College, E1 2AD London, UK;(6) Department of Epidemiology and Statistics, London Hospital Medical College, E1 2AD London, UK
Abstract:
Summary Twelve healthy male volunteers exercised at 200 W on a cycle ergometer for 8 min or until exhausted, if sooner. Retrospectively, subjects fell into two groups. During the last minute of exercise at 200 W, those in group 1 (n = 5) had a mean respiratory exchange ratio (R) of 1.06 (SD 0.01) and were working at a mean of 79% (SD 4%) of their maximum oxygen consumption (
$$dot VO_{2max } $$
) as measured in a separate incremental load test. For subjects in group 2 (n =7),R was 1.31 (SD 0.08) and their
$$dot VO_2 $$
was maximal (mean 101%. SD 3% . Plasma lactate, and adrenaline concentrations rose to higher levels during exercise in subjects in group 2 than in those in group 1. At the finish of exercise, the leucocyte count and the plasma lactate concentration immediately began to fall in subjects in group 1 whereas in group 2 subjects both rose for several minutes before falling. Plasma catecholamine concentrations fell rapidly in both groups during recovery.A preliminary account of this work was presented to a meeting of the Physiological Society (March 1991, London, UK).
Keywords:Leucocytosis  Catecholamines  Lactate  Lymphocytes  Nuutrophils
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