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目的分析4月龄以下小婴儿川崎病的临床发病特点。方法对1999-01—2005-12首都儿科研究所附属儿童医院收治的4月龄以下川崎病患儿30例,进行临床资料回顾性分析。结果4月龄以下小婴儿川崎病以男孩多发,无季节差异;以典型病例多见,但仍有约20%患儿为非典型病例,平均确诊时间长,误诊率较高。结论冠状动脉异常可作为小婴儿非典型川崎病惟一确诊的金指标。同时对于发热>5d,在感染性疾病恢复期再次高热,有明确病毒或细菌感染存在,有预防接种后不明原因发热持续不退的4月龄以下小婴儿应警惕川崎病的发生。

The clinical analysis of Kawasaki disease in little infants under 4 months

Objective For early diagnosis of Kawasaki disease and to decrease the misdiagnosis rate,this article analyze clinical features of Kawasaki disease in the infants.Methods The clinical data of 30 infants aged 1 to 4 months suffering from Kawasaki disease were retrospectively analyzed.Results In this study,the number of boys was more than that of girls.No differences in seasons.The incidence of the typical Kawasaki disease was higher,but the atypical Kawasaki diseases still existed in about 20% patients.The average final diagnosis time of the atypical Kawasaki disease was longer than that of the typical one and the misdiagnosis rate was higher.Conclusion The abnormality of the coronary artery is the only gold index for final diagnosis of the atypical Kawasaki disease.Meanwhile,when the following things happen you ought to think of the disease in the baby who is under 4 months old:fever persisting at least 5 days,ardent fever again during the convalescent period of infection disease,and persistent fever after premonition.