慢性肺心病患者血清维生素E含量测定与病情演变的关系

目的 探讨慢性肺心病患者血清维生素E含量与病情演变的关系。方法 应用国产721分光光度计测定30例慢性肺心病患者（急性加重期和缓解期）及20例健康对照组血清维生素E含量,同步测定8例肺心病急性加重期患者动脉血气,对其结果进行分析。结果 肺心病急性加重期血清维生素E含量明显低于健康对照组,也明显低于缓解期（P＜0．01）,呼吸衰竭程度越重维生素E含量越低。缓解期血清维生素E含量虽有降低,但与健康对照组比较,无统计学意义（P＞0．05）。结论 慢性肺心病急性加重期自由基的产生和清除存在平衡失调。

Measurement of vitamine E in patients with chronic cor pulmonale and the relation with the changes of

Objective To measure the levels of vitamine E in patients with chronic cor pulmonale and discussion on the relation with the changes of the disease. Methods Spectrophotometer 721 was used to measure the serum levels of vitamine E in 30 patients with chronic cor pulmonale and in 20 controls, meanwhile, blood gas analysis was tested in 8 patients of acute exacerbation. Results The levels of vitamine E of the patients in acute exacerbation were much lower than that of controls and the patients in remission ( P <0.01). The levels of vitamine E were lower and lower with the exacerbation of the degree of respiratory failure. Conclusion Dysequilibrium was displayed in the produce and clearance of superoxide in the patients with chronic cor pulmonale during acute exacerbation.