Vertical transmission of HIV in Rio de Janeiro,Brazil |
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Authors: | João Esaú Custódio Cruz Maria Letícia Menezes Jacqueline A Matos Haroldo J Calvet Guilherme A d'Ippolito Marcos M Salgado Luísa T Silva Sonia S Bazin Gabriela R Braga Ricardo C |
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Affiliation: | Infectious Diseases Department, Hospital dos Servidores do Estado, Rio de Janeiro, Brazil. |
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Abstract: | A cohort of 297 HIV-infected pregnant women was followed from January 1996 to December 2001. The overall transmission rate was 3.57% and remained constant over time. Low birth-weight was independently associated with a higher risk of vertical transmission (P=0.0072), whereas a longer duration of antiretroviral drugs during pregnancy was independently associated with a lower risk of transmission (P=0.0084). Further decreases in transmission should be obtained by initiating prophylaxis earlier in pregnancy. |
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