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不稳定性心绞痛患者血清生长分化因子15与TIMI危险评分的相关性
引用本文:邓明尧,吴国平,冯旭霞,罗江宾. 不稳定性心绞痛患者血清生长分化因子15与TIMI危险评分的相关性[J]. 南方医科大学学报, 2011, 31(7): 1277-1278
作者姓名:邓明尧  吴国平  冯旭霞  罗江宾
作者单位:海南省三亚市人民医院心内科;海南医学院附属医院急诊科;
摘    要:
摘要:目的探讨不稳定性心绞痛(unstable angina pcetoris,UAP)患者血清生长分化因子15(GDF-15)与TIMI危险评分的
相关性。方法采用酶联免疫吸附法(ELISA法)检测97例UA患者与30例健康体检者血清GDF-15的表达水平。采用
TIMI危险评分方法将UA患者分为3组,比较各组间GDF-15表达水平差异。分析GDF-15与TIMI危险评分的相关性。
结果UA患者血清GDF-15的表达水平显著高于健康体检者,差异有统计学意义(P<0.01);不同TIMI 危险评分分组之间
血清GDF-15表达水平比较,差异有统计学意义(P<0.01);血清GDF-15表达水平与TIMI危险评分之间存在相关关系。
结论血清GDF-15的表达水平可以作为UA患者危险分层评估指标。

关 键 词:不稳定性心绞痛  生长分化因子15  TIMI危险评分

Correlation between serum growth differentiation factor-15 and TIMI risk scores in patients with unstable angina pectoris
DENG Ming-yao,WU Guo-ping,FENG Xu-xia,LUO Jiang-bin. Correlation between serum growth differentiation factor-15 and TIMI risk scores in patients with unstable angina pectoris[J]. Journal of Southern Medical University, 2011, 31(7): 1277-1278
Authors:DENG Ming-yao  WU Guo-ping  FENG Xu-xia  LUO Jiang-bin
Affiliation:DENG Ming-yao 1,WU Guo-ping 2,FENG Xu-xia 1,LUO Jiang-bin 1 1 Department of Cardiology,Sanya People's Hospital,Sanya 572000,China,2 Emergency Department,Affiliated Hospital of Hainan Medical College,Haikou 570102
Abstract:
Objective To explore the correlation between serum levels of growth differentiation factor-15(GDF-15) and Thrombolysis in Myocardial Infarction(TIMI) risk scores in patients with unstable angina pectoris(UA).Methods The serum levels of GDF-15 in 97 patients with UA and 30 healthy volunteers were measured using enzyme-linked immunosorbent assay(ELISA) and compared between 3 patient groups with different TIMI scores to analyze relationship between serum GDF-15 levels and TIMI risk scores.Results The serum lev...
Keywords:unstable angina pectoris  growth differentiation factor-15  Thrombolysis in Myocardial Infarction risk score  
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