Inhibition of primate spinothalamic tract neurons by stimulation in ipsilateral or contralateral ventral posterior lateral (VPLc) thalamic nucleus |
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| Authors: | K.D. Gerhart R.P. Yezierski T.K. Wilcox A.E. Grossman W.D. Willis |
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| Affiliation: | Marine Biomedical Institute and Departments of Physiology and Biophysics and Anatomy, University of Texas Medical Branch, Galveston, TX 77550 U.S.A. |
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| Abstract: | ![]()
The effects of stimulation in the ventral posterior lateral (VPLc) thalamic nuclei on the activity of primate spinothalamic tract neurons were investigated. All 19 cells studied were strongly inhibited by conditioning trains of stimuli delivered to either ipsilateral or contralateral VPLc. Both background discharges and activity evoked by innocuous or noxious cutaneous stimulation were inhibited. |
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| Keywords: | spinothalamic neurons thalamic stimulation nociception inhibition analgesia |
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