In utero resolution of microcystic congenital cystic adenomatoid malformation after prenatal betamethasone therapy: A report of three cases and a literature review |
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| Authors: | Akiko Yamashita MD Nobuhiro Hidaka MD PhD Ryo Yamamoto MD Soichiro Nakayama MD PhD Jun Sasahara MD PhD Keisuke Ishii MD PhD Nobuaki Mitsuda MD PhD |
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| Affiliation: | Department of Maternal Fetal Medicine, Osaka Medical Center and Research Institute for Maternal and Child Health, Japan |
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| Abstract: | ![]()
Fetal congenital cystic adenomatoid malformation (CCAM) can progress to nonimmune hydrops, and the mortality rate of CCAM with hydrops is reported to be nearly 100%. We describe three microcystic CCAM cases in which the fetal condition improved after maternal betamethasone therapy. The median gestational age at steroid administration was 23 5/7 weeks' gestation. The CCAM decreased in size in all cases. Our series showed a 100% hydrops resolution rate (2/2) and a 100% survival rate (3/3). Our experience suggests the efficacy of betamethasone treatment on fetuses with microcystic CCAM who have fluid collection or are at risk of developing hydrops. © 2014 Wiley Periodicals, Inc. J Clin Ultrasound 43 :451–457, 2015 |
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| Keywords: | sonography congenital cystic adenomatoid malformation hydrops fetalis obstetrics Adzick's classification |
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