肺原发性癌肉瘤21例临床病理分析

原发性肺癌肉瘤21例。本病好发于中老年男性,肺上叶较易累及。中央型略多于周围型,周围型一般肿瘤较大。临床症状出现较晚,明确诊断时往往已有转移。最早出现的转移部位为肺门淋巴结,胸膜及纵隔亦可累及。手术切除后预后较差。 恶性上皮成分通常为鳞癌,其次为腺癌,小细胞未分化癌。间质成分以纤维肉瘤最多风。

Clinopathological Studying in 21 Cases of Pulmonary Carcinosarcomas

Carcinosarcoma is a kind of Tumor from the mixture of malignat epithelial and mesenchymal component. Primary pulmonary carcinosarcoma occurs scarecely. 21 cases of primary carcinosarcoma of lung from 1975 to 1995 in our hospital were reported, with clin-ipathological studying. Most of patients are older man,and no cases appear to have been reported in children. The upper lobes were frequently involved. The central tumors occured slightly more than the peripheral ones. The clinical symptoms of the disease were usually appeared laterly. most patients had metastasis when diagnosed exactly. Spread is initially to hilarlymph nodes,and the tumor may grow through the pleura into the chest wall or penetrate the mediastinum. Prognosis of most cases were poor after operation.Microscopically, most of the epithelial component was squamous carcinoma, then adeno-carcinoma and small cell carcinoma, the majority of stroma elements was fibrosarcoma.