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肾胺酶与心血管疾病研究进展
引用本文:Guo Y,Jiang W. 肾胺酶与心血管疾病研究进展[J]. 中南大学学报(医学版), 2012, 37(5): 537-540. DOI: 10.3969/j.issn.1672-7347.2012.05.021
作者姓名:Guo Y  Jiang W
作者单位:中南大学湘雅三医院心血管内科, 长沙 410013
摘    要:
肾胺酶(renalase)是近年发现的一种由肾脏分泌的胺氧化酶,它可以通过降解儿茶酚胺来调节心功能与血压。肾脏分泌的激素与心血管疾病密切相关,肾胺酶作为反映心肾关系的新标志,具有降压、保护缺血心肌、改善心功能、降解儿茶酚胺等重要作用。

关 键 词:肾胺酶  高血压  心肌缺血  心功能不全  

Research progress with renalase and cardiovascular disease
Guo Yunzhong,Jiang Weihong. Research progress with renalase and cardiovascular disease[J]. Journal of Central South University. Medical sciences, 2012, 37(5): 537-540. DOI: 10.3969/j.issn.1672-7347.2012.05.021
Authors:Guo Yunzhong  Jiang Weihong
Affiliation:Department of Cardiology, Third Xiangya Hospital, Central South University, Changsha 410013, China
Abstract:
Renalase, a novel amine oxidase, is secreted by kidney. It regulates heart function and blood pressure by degrading catecholamines. Hormones secreted by the kidney are associated with cardiovascular disease. Renalase, as a new biomarker of heart and kidney functional correlation, can lower blood pressure, protect ischemic heart muscle, improve heart function and degrade catecholamine.
Keywords:renalase  hypertension  myocardial ischemia  cardiac dysfunction
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