Seral,uterine and fetal salicylate concentrations after oral administration |
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Authors: | M. Grönroos M. Haataja E. Honkonen M. Anttila |
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Affiliation: | Department of Obstetrics and Gynecology and Department of Internal Disease, University Central Hospital and Farmos Group, Research Center, Turku, Finland |
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Abstract: | Salicylate concentrations in serum, endometrium, myometrium and fetus were determined 3 h after an oral dose of 1 000 mg of acetylsalicylic acid. The material consisted of 19 females (11 for legal abortion and 8 for operative treatment of fibroids). Tissue salicylate concentrations were at a level at which prostaglandin synthetase is inhibited. |
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Keywords: | salicylate concentrations uterine fetal |
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