| EB病毒感染与T细胞淋巴瘤的发生 |
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| 引用本文： | 谢晓利,甘润良.EB病毒感染与T细胞淋巴瘤的发生[J].白血病．淋巴瘤,2004,18(1):312-315. |
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| 作者姓名： | 谢晓利 甘润良 |
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| 作者单位： | 衡阳,南华大学医学院肿瘤研究所,湖南,421001; |
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| 摘 要： | EB病毒(EBV)是一种DNA肿瘤病毒,以往有关EBV致瘤机制的研究主要集中在B淋巴细胞.日前检测发现人类T细胞淋巴瘤也存在EBV感染.近年来研究表明EBV感染可转化T淋巴细胞,EBV可能在T细胞淋巴瘤的发生中起重要作用.观察LMP1在T细胞中的分子生物效应,有助于了解T淋巴细胞中EBV的感染途径、感染方式以及T细胞淋巴瘤的发生机制.
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| 关 键 词： | 疱疹病毒4型 人 淋巴瘤 T细胞 |
Epstein-Barr virus infection and development of T-cell lymphoma |
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| XIE Xiao-li,GAN Run-liang.Epstein-Barr virus infection and development of T-cell lymphoma[J].Journal of Leukemia & Lymphoma,2004,18(1):312-315. |
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| Authors: | XIE Xiao-li GAN Run-liang |
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| Abstract: | Epstein-Barr virus (EBV) is a kind of DNA tumor virus. Previous Studies on the tumorigenic mechanism of EBV mainly focus on human B lymphocyte. Now there are evidences that EBV exists in human T-cell lymphoma. Exploration in recent years show that EBV could infect T lymphocyte and likely play an important role in the pathogenesis of T-cell lymphoma. Investigation of molecular biological effect of LMP1 in T cell will be helpful for us to understand the approach and mode of EBV infecting T lymphocyte as well as the mechanism of T-cell lymphoma development. |
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| Keywords: | Herpesvinus 4 humanLymphoma T-cell |
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