鼻神经内分泌癌6例报告

目的 研究鼻神经内分泌癌这一少见病的临床特点、病理、治疗及预后因素。方法 对本院收治的6例鼻神经内分泌癌的临床资料进行回顾性分析。6例患者均采用^60Co照射为主,2例加鼻侧切开术。结果 2例在治疗后6个月的死亡,1例放疗后13个月发现骨转移正在当地医院化疗,1例放疗后15个月发现肝转移,目前中医治疗。仅2例治疗后随访14月无瘤生存。结论 鼻神经内分泌癌恶性程度高,预后差,提高对本病的认识,早发现,早诊断并采用综合治疗可改善本病的预后。

Nasal Neuroendocrine Carcinoma:A Report of 6 Cases

Purpose To discuss the clinical characteristics,pathology,treatment and prognostic factors of patients with nasal neuroendocrine carcinoma(NEC). Methods Six cases of nasal neuroendocrine carcinomas were analyzed.All patients underwent radiotherapy with 60 Co.Two of these had lateral rhinotomy. Results Two patients died within 6 months.One patient had bone metastases 13 months later.One patient had liver metastases 15 months later. Conclusions Nasal neuroendocrine carcinoma is extremely uncommon tumor and is aggressive with rather poor prognosis.Early diagnosis and treatment as well as combined modality therapy could improve prognosis.