肝硬化患者两种肝储备功能评价方法的比较

目的 比较MELD和Child-Pugh分级评估肝硬化患者肝储备功能的差异,分析两体系的相关性.方法 回顾性分析92例肝炎后肝硬化患者入院时的MELD和Child-Pugh肝功能功能分级分值,研究两体系的相关性,通过ROC曲线分析比较两体系的差异.结果 MELD和Child-Pugh两体系显著相关(r=0.669,P<0.000),3个月生存期的患者两体系ROC曲线面积有显著性差异(P<0.05),而生存期超过6个月的患者MELD较Child-Pugh无显著性差异(P>0.05).结论 MELD和Child-Pugh均可较精确评估生存期预后;MELD适宜评估危重患者,而对预后超过6个月的患者无明显优势.

Comparison of MELD score and Child-Pugh grading in patients with liver Cirrhosis

Objective To compare the differences between MELD and Child-Pugh grading in assessing of hepatic functional reserve in patients with cirrhosis,and analyse the correlation of two systems.Methods Retrospective analysis was made on 92 cases of hepatitis cirrhosis hospitalized with the MELD and Child-Pugh score by ROC curve,the difference and relation between two systems were compared.Results MELD and Child-Pugh system were significantly correlated(r=0.669,P < 0.000),3-month survival in patients with two systems ROC curve areas was significantly different(P < 0.05),while the MELD in patients survived more than 6 months was not significantly different compared with Child-Pugh(P>0.05).ConclusionMELD and Child-Pugh can accurately assess the prognosis of survival for patients with hepatic cirrhosis,and MELD is suitable for assessment of risk,heavy patients,not for those survived more than 6 months.