罗格列酮联合二甲双胍治疗2型糖尿病疗效观察

目的:观察罗格列酮联合二甲双胍治疗2型糖尿病的临床疗效。方法:64例符合2型糖尿病诊断的门诊患者随机分为:治疗组32例,应用罗格列酮4mg/次,1日1次;二甲双胍片0.25mg/次,1日3次。对照组32例服用二甲双胍片0.5mg/次,1日3次。疗程均为6周。结果:治疗组患者餐前血糖及餐后2小时血糖与其进入临床观察前不同,差异有显著性P<0.05。对照组则无此变化,P>0.05。结论:罗格列酮与二甲双胍合用治疗2型糖尿病疗效明显比单用二甲双胍为好。

Observation of the curative effect of rosiglitazone combined with mefformin in type 2 diabetes

Objective:To observe the curative effect of rosiglitazone combined with metformin in the treatment of type 2 diabetes.Methods:64 outpatients corresponding to type 2 diabetes were divided into two groups at random,with 32 cases in each group.The treatment group(group A) was treated with rosigilitazone tablets 4 mg orally once a day and metformin tablets 0.25 g three times a day,while the control group(group B) with metformin tablets 0.5g three times a day.The course of treatment in both groups was six weeks.Results:In group A,the blood glucose of the patients was changed before meal and two hours after meal compared with that of the patients before clinical observation,with significant difference(P<0.05).However,there was no any change im group B(P>0.05).Conclusion:The curative effect of rosiglitazone combined with melformin is far better than that only with metformin in type 2 diabetes.