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| 中心型肥胖与头颈癌的关系 | |
| 引用本文： | 李超友,王安洋,薛刚. 中心型肥胖与头颈癌的关系[J]. 山东大学耳鼻喉眼学报, 2022, 36(2): 120-125. DOI: 10.6040/j.issn.1673-3770.0.2021.137 |
| 作者姓名： | 李超友 王安洋 薛刚 |
| 作者单位： | 河北北方学院 耳鼻咽喉头颈外科教研室/张家口市甲状腺癌精准诊疗重点实验室, 河北 张家口 075000 |
| 基金项目： | 河北省财政厅专科能力建设和带头人培养项目(361009) |
| 摘 要： | 随着全球超重人口数量和比例不断增加,肥胖已成为全球最严重的卫生保健问题之一。肥胖不仅与高血压、高脂血症、糖尿病、胰岛素抵抗等多种疾病关系密切,而且与头颈癌发生的高风险和高死亡率之间可能存在因果关系。重点综述中心型肥胖与头颈癌之间的关系,以及头颈癌患者脂质代谢异常的分子机制,为未来将肥胖作为临床预防头颈癌的新靶点提供新思路。 |
| 关 键 词： | 中心型肥胖 头颈癌 高脂饮食 体质量指数 脂质代谢异常 |
The relationship between central obesity and head and neck cancer |
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| LI Chaoyou,WANG Anyang,XUE Gang. The relationship between central obesity and head and neck cancer[J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2022, 36(2): 120-125. DOI: 10.6040/j.issn.1673-3770.0.2021.137 | |
| Authors: | LI Chaoyou WANG Anyang XUE Gang |
| Affiliation: | Department of Otorhinolaryngology & Head and Neck Surgery, Hebei North University /Key Laboratory of Thyroid Cancer Precision Diagnosis and Treatment of Zhangjiakou, Zhangjiakou 075000, Hebei, China |
| Abstract: | With the increasing number and proportion of obese and overweight people worldwide, obesity has become one of the most globally serious health care problems. Obesity has also been thought to be the cause of many diseases, including hypertension, hyperlipemia, diabetes and insulin resistance. Interestingly, a high risk and mortality rate in head and neck cancer patients have been associated with obesity. Thus, this review focused on the relationship between obesity and head and neck cancer, investigating the molecular mechanism of abnormal lipid metabolism in these patients. Therefore, preventive obesity may be as a new insight in the management of patients with head and neck cancer. |
| Keywords: | Central Obesity Head and neck cancer High-fat diet Body mass index Abnormal lipid metabolism |
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