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| 阻塞性睡眠呼吸暂停低通气综合征与亚临床动脉粥样硬化 | |
| 引用本文： | 韩莹莹,李延忠. 阻塞性睡眠呼吸暂停低通气综合征与亚临床动脉粥样硬化[J]. 山东大学耳鼻喉眼学报, 2022, 36(2): 126-132. DOI: 10.6040/j.issn.1673-3770.0.2022.011 |
| 作者姓名： | 韩莹莹 李延忠 |
| 作者单位： | 山东大学), 山东 济南 250012 |
| 基金项目： | 国家自然科学基金(82000968);山东省自然科学基金(ZR2018MH017,ZR201911030252) |
| 摘 要： | 阻塞性睡眠呼吸暂停低通气综合征是心血管疾病的独立危险因素，严重影响患者的生命质量和生存时间，也是可以改变的心血管疾病危险因素之一。动脉粥样硬化是造成心血管疾病的病理基础，而大量研究发现阻塞性睡眠呼吸暂停低通气综合征与亚临床动脉粥样硬化相关，综述阻塞性睡眠呼吸暂停低通气综合征与亚临床动脉粥样硬化的研究进展，并梳理其中发病机制，为阻塞性睡眠呼吸暂停低通气综合征患者动脉粥样硬化的预防和早期干预提供依据。 |
| 关 键 词： | 阻塞性睡眠呼吸暂停低通气综合征 亚临床动脉粥样硬化 颈动脉内膜中层厚度 发病机制 |
Obstructive sleep apnea hypopnea syndrome and subclinical arteriosclerosis |
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| HAN Yingying,LI Yanzhong. Obstructive sleep apnea hypopnea syndrome and subclinical arteriosclerosis[J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2022, 36(2): 126-132. DOI: 10.6040/j.issn.1673-3770.0.2022.011 | |
| Authors: | HAN Yingying LI Yanzhong |
| Affiliation: | Department of Otorhinolaryngology, Qilu Hospital of Shandong University / NHC Key Laboratory of Otolaryngology (Shandong University), Jinan 250012, Shandong, China |
| Abstract: | Objective sleep apnea hypopnea syndrome is an independent risk factor for cardiovascular disease, and seriously affects the quality of life and even survival time of patients. It is one of the modifiable risk factors for cardiovascular disease. Atherosclerosis is involved in the pathogenesis of cardiovascular disorders. While a large number of studies have found that obstructive sleep apnea hypopnea syndrome is associated with subclinical atherosclerosis. Our study aims to understand the clear role of obstructive sleep apnea hypopnea syndrome in subclinical arteriosclerosis, and therefore provide evidence for the prevention and early intervention of atherosclerosis in patients with obstructive sleep apnea hypopnea syndrome. |
| Keywords: | Obstructive sleep apnea hypopnea syndrome Subclinical atherosclerosis Carotid intima-media thickness Pathogenesis |
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