| 几种咪唑类外用抗真菌药接触性皮炎的初步研究 |
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| 引用本文： | 李林峰,王宝华,孙祥银, 林幼青,陈学荣,李世荫.几种咪唑类外用抗真菌药接触性皮炎的初步研究[J].北京大学学报(医学版),1994(4). |
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| 作者姓名： | 李林峰 王宝华 孙祥银 林幼青 陈学荣 李世荫 |
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| 作者单位： | 北京医科大学第三医院皮肤科 山东省潍坊市皮肤病防治所(李林峰，王宝华，孙祥银)，( 林幼青，陈学荣，李世荫) |
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| 摘 要： | 用３种常用外用咪唑类抗真菌药，达克宁霜（咪康唑）、联苯苄唑霜及癣敌软膏（益康唑）对１８５例有外用此类药物史的皮肤病病人进行了斑贴试验。结果斑试刺激反应及过敏反应阳性率分别为３．８％及４．３％，说明此类药物是常见的致敏原及刺激原之一。抗真菌剂致敏可出现急性接触性皮炎，应与真菌病加重相鉴别。斑贴试验可以诊断抗真菌剂接触性皮炎，并区分刺激反应与过敏反应。
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| 关 键 词： | 抗真菌药，咪唑类，接触性皮炎 |
CONTACT DERMATITIS DUE TO SOME TOPICAL IMIDAZOLE ANTIFUNGAL DRUGS |
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| Institution: | Department of Dermatology,The Third Hospital Li Linfeng,et
al |
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| Abstract: | Three commonly used topical imidazole antifunga drugs,
miconazole nitrate cream, bifonazolecream and econazole nitrate
ointment were patch tested in 185 randomly selected skin disease
patientswho had used at least one kind of imidazole before. The
positive rate is3.8%and 4.3%for irritantand allergic reactions
respectlvely. The results indicated that when deterioration was
found during theimidazole treatment, contact dermatitis should be
considered and patient should be patch tested. |
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| Keywords: | Antifungal drugs lmidazole Contact dermatitis |
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