二羧乙基锗倍半氧化物对消化性溃疡的疗效

将消化性溃疡138例分为二羧乙基锗倍半氧化物组(CEG)甲氰咪胍和对照组,观察了前者的近期疗效.CEG治疗后一周、六周的腹痛缓解率分别为53.0％和92.0％,略高于对照组,但无显著性差异.治疗六周后溃疡愈合率(92％)亦稍高于对照组(82％),但无显著差异.治疗前后胃酸排泌量及血清胃泌素浓度无明显变化.部分病例出现恶心(5例)、食欲不振(4例)及腹泻(3例),但未影响治疗.

Therapeutic Effeet of Carboxy Ethyl Germanium Sesquiox ide on Peptic Ulcer

138 patients with peptic ulcer were randomly divided into therapeutic group treated with carboxy ethyl germanium sesquioxide(CEG)and the control group treated with cimetidine,to investigate the short-term therapeutic effect. After using CEG for one week and for 6 weeks,the rates of relieving abdomin- algia were 53% and 92% respetively.The rate of relieving abdominalgia in CEG group was higher than that in the control,but there was no significant difference.After CEG therapy for 6 weeks,the healing rate(92%)of ulcer under gastroscopy was higher than that of the control(82%),but there was no significant difference(P>0.05).There was no significant difference in secretive output of hydrochloric acid and gastrin concentration in serum before and after the therapy.Some patients presented with nausea(5 cases), poor appetite(4 cases)and diarrhoea(3 cases),and that did not affect the process of the therapy.