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急性黄疸型病毒性肝炎血浆高密度脂蛋白亚组份的变化
引用本文:洪嘉玲,朱汉明许春玲,杨自成,王启南. 急性黄疸型病毒性肝炎血浆高密度脂蛋白亚组份的变化[J]. 武汉大学学报(医学版), 1989, 0(1)
作者姓名:洪嘉玲  朱汉明许春玲  杨自成  王启南
作者单位:湖北医学院生化教研室,湖北医学院生化教研室,湖北医学院附二医院传染病学教研室,湖北医学院附二医院传染病学教研室
摘    要:急性黄疸型病毒性肝炎患者血浆 HDL 及 HDL 亚组份所台 Ch 和Apo—AI 皆明显降低,在 HDL—C 中 HDL—C 降低尤甚,其 Ch/Apo-AI 比值降低,随着病情好转上述指标的含量递增,但在 SGPT 已恢复正常时,HDL 及其亚组份所含 Apo—AI 与正常人相比仍处于低值,该指标对于判断急黄肝患者肝功能状态及预后可能更为优越。

关 键 词:脂蛋白类  高密度/代谢  胆甾醇/代谢  脱辅基脯蛋白类  免疫电泳

Variability of High-Density Lipoprotein Subfractions in Plasma of Patients with Acute Icteric Virulent Hepatitis
Hong Jialing. Variability of High-Density Lipoprotein Subfractions in Plasma of Patients with Acute Icteric Virulent Hepatitis[J]. Medical Journal of Wuhan University, 1989, 0(1)
Authors:Hong Jialing
Abstract:HDL in plasma of 22 patients with acute icteric virulent hepatitis was determined.Ch and Apo-A1 of HDL and subfractions ware decreased signi- ficantly.The HDL_3-C/HDL_2-C was increased and Ch/Apo-A1 in HDL_2 was decreased.As the clinical symptoms were reversed,so was what men- tioned above.If we used SGPT activity as an index,Apo-A1 of HDL and HDL subfractions were still lower than those of the healthy aubjeets when SGPT activity was normal.This index can provide a convincing judyment for liver function and prognosis of disease.
Keywords:lipoprotein  HDL/ME  cholesterol/ME  apolipoproteins  immunoelectrophoresis
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