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抑郁症患者治疗前后执行功能变化的研究
引用本文:鞠海燕,江玉娟,杨怡,刘立静,宋京花. 抑郁症患者治疗前后执行功能变化的研究[J]. 疑难病杂志, 2011, 10(9): 653-655. DOI: 10.3969/j.issn.1671-6450.2011.09.005
作者姓名:鞠海燕  江玉娟  杨怡  刘立静  宋京花
作者单位:1. 河北省沧州市中心医院,061001
2. 沧州医学高等专科学校,061001
3. 河北省盐山县人民医院,061000
摘    要:目的探讨抑郁症患者治疗前后执行功能的变化。方法 60例抑郁症患者(抑郁组)于治疗前和治疗8周末进行威斯康星卡片分类测验(WCST)、Stroop色词测验、汉密尔顿抑郁量表(HAMD-17)、汉密尔顿焦虑量表(HAMA)评定,同时设健康对照组60例进行比较。结果抑郁组治疗前WCST测查评分较健康对照组差(P<0.01);治疗后较治疗前有显著改善(P<0.01)。Stroop测查抑郁组治疗前Stroop-CW正确数、Stroop-CW改正数较健康对照组差(P<0.05,P<0.01);治疗后有改善,但与治疗前比较差异无统计学意义(P>0.05);Stroop测查抑郁组治疗后Stroop-CW正确数、改正数仍较健康对照组差(P<0.05,P<0.01)。结论抑郁障碍患者发病期存在执行功能障碍,治疗后执行功能障碍随症状改善而改善,但仍低于健康对照组。

关 键 词:抑郁障碍  执行功能  神经心理测查

Change of executive function before and after treatment in depressive disorder patients
JU Hai-yan,JIANG Yu-juan,YANG Yi,et al.. Change of executive function before and after treatment in depressive disorder patients[J]. Journal of Difficult and Complicated Cases, 2011, 10(9): 653-655. DOI: 10.3969/j.issn.1671-6450.2011.09.005
Authors:JU Hai-yan  JIANG Yu-juan  YANG Yi  et al.
Affiliation:JU Hai-yan~*,JIANG Yu-juan,YANG Yi,et al.* Cangzhou Central Hospital,Hebei Province,Cangzhou 061001,China
Abstract:Objective To investigate the variance of executive function in depressive disorders patients after treatment. Methods Sixty depressive disorders patients was analyzed by Wisconsin card sorting test(WCST),Stroop chromo word test,Hamilton's depression scale(HAMD-17),Hamilton anxiety scale(HAMA) before treatment and 6 weeks after treatment.60 normal healthy people was enrolled as control group.Results Wisconsin card sorting test grade of depressive disorders group was lower than that of normal control group be...
Keywords:Depressive disorder  Executive function  Nerve psychology survey  
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